Overexpression of neuropeptide Y decreases responsiveness to neuropeptide Y
نویسندگان
چکیده
منابع مشابه
Neuropeptide Y GERALD
NEUROPEPTIDE Y (NPY) was identified as a neuropeptide that is colocalized and coreleased with the neurotransmitter norepinephrine from sympathetic nerve terminals. In this regard, a large body of research on NPY focused on its role in autonomic physiology and pharmacology as a potentiator of the postsynaptic actions of norepinephrine. However, with the increased understanding of the genes and t...
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NEUROPEPTIDE Y (NPY) was identified as a neuropeptide that is colocalized and coreleased with the neurotransmitter norepinephrine from sympathetic nerve terminals. In this regard, a large body of research on NPY focused on its role in autonomic physiology and pharmacology as a potentiator of the postsynaptic actions of norepinephrine. However, with the increased understanding of the genes and t...
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Neuropeptide Y (NPY) is a 36-amino acid peptide with structural similarities to peptide YY (PYY) and pancreatic polypeptide (PP). NPY, one of the most abundant neuropeptides known, is widely distributed throughout the central and peripheral nervous systems, while PYY and PP are predominantly distributed in the endocrine cells of the intestine and pancreas, respectively. Five NPY receptor subtyp...
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The Neuropeptide Y (NPY) is a peptide of 36 amino acids, similar to the peptide YY (PYY) and to the pancreatic polypeptides (PP). At first, separated from the pig brain, the NPY is well-distributed in the mammals at the level of the central and peripheric nervous system. This neurotransmitter is present in strong concentrations in the nervous fiber of the brain, but equally as strong in the hea...
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To investigate the release of neuropeptide Y (NPY) from the pheochromocytomas, we studied the relationship between the plasma and tumor tissue immunoreactive (IR) NPY concentrations in 13 patients with pheochromocytoma and measured the IR-NPY concentration in plasma samples obtained by catheter from several veins (jugular veins, superior vena cava, renal veins, adrenal veins and inferior vena c...
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ژورنال
عنوان ژورنال: Neuropeptides
سال: 2020
ISSN: 0143-4179
DOI: 10.1016/j.npep.2019.101979